Server Error in '/thumb' Application.

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Line 1:  <%@ Application Language="VB" %>
Line 2:  <script runat="server">
Line 3:  	Public Shared LogFile As New ScriptUtilities.LogFile
Line 4:  	Public Shared LogFile2 As New ScriptUtilities.LogFile
Line 5:  	Sub Application_Start(ByVal sender As Object, ByVal e As EventArgs)

[COMException (0x800703fa): Retrieving the COM class factory for component with CLSID {F2CE8675-3E8C-45F0-91A8-8EBDD7258FAB} failed due to the following error: 800703fa Illegal operation attempted on a registry key that has been marked for deletion. (Exception from HRESULT: 0x800703FA).]
   ASP.global_asax..cctor() in E:\InetPub\wwwroot\Utils\thumb\global.asax:3

[TypeInitializationException: The type initializer for 'ASP.global_asax' threw an exception.]
   ASP.global_asax..ctor() +0

[TargetInvocationException: Exception has been thrown by the target of an invocation.]
   System.RuntimeTypeHandle.CreateInstance(RuntimeType type, Boolean publicOnly, Boolean noCheck, Boolean& canBeCached, RuntimeMethodHandleInternal& ctor, Boolean& bNeedSecurityCheck) +0
   System.RuntimeType.CreateInstanceSlow(Boolean publicOnly, Boolean skipCheckThis, Boolean fillCache, StackCrawlMark& stackMark) +159
   System.RuntimeType.CreateInstanceDefaultCtor(Boolean publicOnly, Boolean skipCheckThis, Boolean fillCache, StackCrawlMark& stackMark) +233
   System.Activator.CreateInstance(Type type, Boolean nonPublic) +75
   System.RuntimeType.CreateInstanceImpl(BindingFlags bindingAttr, Binder binder, Object[] args, CultureInfo culture, Object[] activationAttributes, StackCrawlMark& stackMark) +1097
   System.Activator.CreateInstance(Type type, BindingFlags bindingAttr, Binder binder, Object[] args, CultureInfo culture, Object[] activationAttributes) +212
   System.Activator.CreateInstance(Type type, BindingFlags bindingAttr, Binder binder, Object[] args, CultureInfo culture) +19
   System.Web.HttpRuntime.CreateNonPublicInstance(Type type, Object[] args) +60
   System.Web.HttpApplicationFactory.GetSpecialApplicationInstance(IntPtr appContext, HttpContext context) +148
   System.Web.Hosting.PipelineRuntime.InitializeApplication(IntPtr appContext) +303

[HttpException (0x80004005): Exception has been thrown by the target of an invocation.]
   System.Web.HttpRuntime.FirstRequestInit(HttpContext context) +664
   System.Web.HttpRuntime.EnsureFirstRequestInit(HttpContext context) +90
   System.Web.HttpRuntime.ProcessRequestNotificationPrivate(IIS7WorkerRequest wr, HttpContext context) +189